Description

Sartelli et al reported a sepsis severity score for patients with complicated intra-abdominal infections. This can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals from around the world and members of the World Society of Emergency Surgery (WSES).


Patient selection: sepsis associated with complicated intra-abdominal infection (localized or diffuse peritonitis) in adults (age > 18 years)

 

Parameters:

(1) clinical status on admission

(2) setting of acquisition

(3) origin of intra-abdominal infection

(4) delay in source control

(5) age in years

(6) immunosuppression (chronic corticosteroids, immunosuppressant agents, chemotherapy, etc)

 

Parameter

Finding

Points

clinical status on admission

severe sepsis

3

 

septic shock

5

 

other

0

setting of acquisition

healthcare associated

2

 

other

0

origin of infection

colonic non-diverticular perforation peritonitis

2

 

small bowel perforation peritonitis

3

 

diverticular diffuse peritonitis

2

 

post-operative diffuse peritonitis

2

 

other

0

delay in source control

none

0

 

delayed (preoperative duration of peritonitis > 24 hours)

3

age

<= 70 years

0

 

> 70 years

2

immunosuppression

no

0

 

yes

3

 

total score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 18

• The higher the score the more severe the patient's condition and the greater the risk of mortality.

 

Score

Mortality

0 to 3

0.6%

4 to 6

6.3%

7 to 18

42%

9 to 18

56%

11 to 18

68%

13 to 18

81%

 

Performance:

• A cutoff of 5.5 had a sensitivity of 89% and specificity of 84% for mortality. The positive likelihood ratio was 5.4.


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