medical decision support medical decision support
Sign In

Wisconsin Index (WIN) of Mazeh et al for Evaluating a Patient with Hyperparathyroidism

Description

Mazeh et al reported a nomogram to predict the presence or additional hyperfunctioning parathyroid glands during parathyroidectomy. This is based on a Wisconsin Index and weight of the removed parathyroid glands. The authors are from the University of Wisconsin in Madison.


Patient selection: hyperparathyroidism

 

Parameters:

(1) preoperative serum total calcium in mg/dL

(2) preoperative parathyroid hormone level in pg/dL

(3) parathyroid gland weight in milligrams

 

index =

= (serum calcium) * (preoperative parathyroid level)

 

Index

Level

< 800

low

800 to 1600

medium

> 1600

high

 

Confirmation of no further hyperfunctioning parathyroid glans was a >= 50% decrease in intraoperative PTH levels after removal of a parathyroid gland.

 

Weight

High

Medium

Low

100

97

94

83

200

80.7

62.2

38.5

300

74

43.1

18.7

400

67.3

33

14.7

500

62.4

23.9

8.6

600

55

18.3

8.1

800

38.5

9.5

4.6

1000

19

2

0

 

This is approximated by:

 

Gland Weight

Probability Multiple Glands for High Curve

100 to 200

113.3-(0.163 * (weight))

200 to 1000

(-0.00003129 * ((weight)^2)) - (0.03826 * (weight)) + 88.84

 

 

Gland Weight

Probability Multiple Glands for Medium Curve

100 to 300

(0.000434 * ((weight)^2)) - (0.428 * (weight)) + 132.5

300 to 1000

(0.00005865 * ((weight)^2)) - (0.1331 * (weight)) + 77.08

 

 

Gland Weight

Probability Multiple Glands for Low Curve

100 to 500

(-0.00000222 * ((weight)^3)) + (0.002662 * ((weight)^2)) - (1.094 * (weight)) + 168.1

500 to 1000

(-0.00002121 * ((weight)^2)) + (0.01422 * (weight)) + 6.942

 


To read more or access our algorithms and calculators, please log in or register.

Specialty