The World Health Organization (WHO) published criteria for describing the response of metastatic bone cancer to therapy.
Imaging Study (X-Ray or Scan)
Response
complete disappearance of all lesions for >= 4 weeks
complete
partial decrease in size of lytic lesions for >= 4 weeks
partial
recalcification of lytic lesions for >= 4 weeks
decreased density for blastic lesions for >= 4 weeks
no change in size, number or appearance of bone lesions for >= 8 weeks
no change (stable disease)
increase in size of lesions
progressive
appearance of new lesions
where:
• The patient should be evaluated for several weeks after therapy prior to classification because of the relative slow response of bone lesions.
• Caution should be used in interpreting lesions with compression and fracture.
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Specialty: Hematology Oncology, Surgery, general
ICD-10: ,
