A patient may be suspected of having Kallman Syndrome (KS) if clinical and laboratory findings are noted.


Reasons to suspect Kallmann syndrome:

(1) family history

(2) male infant with (micropenis OR cryptorchidism) AND (no increase in FSH, LH and testosterone at 4-20 weeks of age)

(3) lack of sexual development at the time of puberty (small testes and absent virilization in males; primary amenorrhea and lack of breast development in females)

(4) low serum LH, FSH and sex hormones (testosterone in male, estrogen and progesterone in female) after normal age of puberty

(5) anosmia or hyposmia (no or reduced sense of smell)


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