Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is uncommon but should be suspected when certain findings are identified.


When to suspect CPVT:

(1) exercise-induced polymorphic ventricular arrhythmias

(2) syncope that occurs during physical activity or acute emotion

(3) ventricular fibrillation during acute stress

(4) history of palpitations and dizziness precipitated by exercise or acute emotion

(5) absence of structural cardiac abnormalities

(6) sudden cardiac death triggered by exercise or acute emotion

(7) exercise-induced supraventricular tachycardia or atrial fibrillation


When CPVT is inherited, then other family members may show one or more of these findings.


The ECG may be normal between episodes or show nonspecific findings. The abnormalities can be identified by an exercise stress test, with ventricular arrhythmias appearing once the heart rate exceeds 100-120 beats per minute.


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