Warfarin Resistance Testing (Coumadin)

Are you evaluating a patient who requires a very large daily dose of warfarin in order to achieve a therapeutic INR?

Yes

Is the serum warfarin level elevated?

Has the patient been noncompliant in taking the warfarin?

Yes

Does the patient have malabsorption or diarrhea?

Yes

Is the patient taking a drug that can induce warfarin metabolism?

Yes

Does the patient have a condition that results in increased metabolism or clearance of warfarin?

Yes

Has there been a laboratory error in the prothrombin test or calculation of the INR?

Yes

Does the patient have a hereditary resistance to warfarin, shared by other family members?

Does the patient have a high vitamin K intake from the diet?

Yes

Is the patient receiving parenteral nutrition?

Yes

Is the patient taking an herbal remedy?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Number of possible causes for warfarin resistance

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Risk Factors of Hylek et al for Excessive Warfarin Anticoagulation
- Algorithm of Dunn for the Perioperative Management of a Patient Receiving Oral Anticoagulation
Clinical Diagnosis, Including Family History For Genetics
- Warfarin Resistance Associated with Poor Intestinal Absorption

Therapy

Selection
- Algorithm of Dunn for the Perioperative Management of a Patient Receiving Oral Anticoagulation
Pharmacogenetics
- Regression Model of Wells et al for Predicting Warfarin Dose Using Pharmacogenetics
Drug Interactions
- Daily Warfarin Dosage Adjustment for Patient Receiving Long-Term Amiodarone Therapy
Dosage Calculations
Dosage Adjustments
Failure Handling And Therapy Escalation
- Risk Factors of Hylek et al for Excessive Warfarin Anticoagulation
- Warfarin Resistance Associated with Poor Intestinal Absorption

Monitoring

Adverse Effects
- Risk Factors of Hylek et al for Excessive Warfarin Anticoagulation
Overdose And Reversal
- Risk Factors of Hylek et al for Excessive Warfarin Anticoagulation

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10

Warfarin (Coumadin) Resistance Testing

Purpose: To evaluate a patient who appears to be warfarin resistant.

Evaluation

Results

Please fill out required fields.

MedicalAlgorithms.com APIs

Power Your Solutions with 5,000+ Automated Medical Analytics

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10