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Warfarin (Coumadin) Resistance Testing

Purpose:	To evaluate a patient who appears to be warfarin resistant.
Specialty:	Hematology Oncology Clinical Laboratory Clinical Pharmacology
Objective:	clinical diagnosis, including family history for genetics, laboratory tests, failure handling and therapy escalation, response to therapy, drug levels, overdose and reversal
ICD-10:	I74, I81, I82, O88
Description:	Warfarin resistance refers to the need for high doses of warfarin (20 mg or more per day) to achieve a therapeutic increase in the prothrombin time (PT) and INR.

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