VTE-BLEED Risk Score of Klok et al for Prediction of Bleeding in a Patient Receiving Anticoagulation Therapy for Venous Thromboembolism

Description

Klok et al reported the VTE-BLEED score for prediction of the risk of bleeding in a patient receiving oral anticoagulants for venous thromboembolism. The authors are from Gutenberg University, McMaster University, and the University of Thrace.

Patient selection: anticoagulation therapy for venous thromboembolism

Outcome: bleeding during stable anticoagulation therapy

Parameters:

(1) active cancer

(2) sex and uncontrolled arterial hypertension (systolic blood pressure >= 140 mm Hg

(3) anemia

(4) history of bleeding

(5) age in years

(6) renal dysfunction (creatinine clearance 30-50 mL/min)

Parameter	Finding	Points
active cancer	no	0
	yes	2
sex and blood pressure	male with uncontrolled hypertension	2
	other	0
anemia	no	0
	yes	1.5
history of bleeding	no	0
	yes	1.5
age in years	< 60 years	0
	>= 60 years	1.5
renal dysfunction	no	0
	yes	1.5

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 10

Total Score	Bleeding Risk Category	Rate of Bleeding
0 or 1	low	2.8%
2 to 10	high	12.6%

Performance:

• The area under the ROC curve is 0.72.

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VTE-BLEED Risk Score of Klok et al for Prediction of Bleeding in a Patient Receiving Anticoagulation Therapy for Venous Thromboembolism

Description

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