DiGeorge Syndrome may be associated with immunodeficiency. During a primary Varicella Zoster infection (chickenpox) there may be disseminated disease to include the appendix.
Patient selection: DiGeorge or other immunodeficiency syndrome, primary chickenpox infection
Clinical features:
(1) prolonged duration of the chickenpox
(2) right lower quadrant pain
(3) clinical evidence of appendicitis
(4) PCR or other evidence of Varicella Zoster in appendiceal tissue
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