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Use of ZAP-70 and Immunoglobulin Heavy Chain Gene Mutation Status to Predict Therapy Free Survival in a Patient with Chronic Lymphocytic Leukemia

Specialty:

Hematology Oncology

Objective:

ICD-10:

Description:

Rassenti et al evaluated patients with chronic lymphocytic leukemia (CLL) for the relationship between ZAP-70 and immunoglobulin heavy chain gene mutation (IgVH) status and therapy-free survival. This can help identify patients with more aggressive disease who may require closer monitoring and more aggressive management. The authors are from the Chronic Lymphocytic Leukemia Research Consortium.

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