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Use of Vitamin K to Reverse Warfarin-Associated Coagulopathy

Specialty:

Hematology Oncology
Clinical Laboratory
Clinical Pharmacology
Clinical Laboratory

Objective:

ICD-10:

Description:

A person receiving warfarin as an oral anticoagulant may develop a coagulopathy if excessive drug is taken or a significant change in diet occurs. Administration of vitamin K1 (phytonadione) can reverse the coagulopathy but may result in under-anticoagulation for a period of time. The proper intervention depends on the patient's clinical status and situation.

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