Use of the 1996 Updated Sheffield Table for Primary Prevention of Coronary Disease


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Statins (inhibitors of hydroxymethyl-glutaryl-coA-reductase) have been shown to be beneficial if the serum cholesterol averages at least 5.5 mmol/L and if the risk of myocardial infarction or coronary death is at least 1.5% per year. The Sheffield tables were designed to give a simple estimate of coronary heart disease risk and to help guide treatment with statins for prevention of primary coronary heart disease. They are based on a logistic regression equation for predicting coronary risk based on the Framingham population. They were published in 1995 and subsequently updated in 1996.

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