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Use of Prothrombin Complex Concentrate to Reverse the Effects of a Vitamin K Antagonist

Specialty:

Hematology Oncology
Clinical Laboratory
Clinical Pharmacology
Clinical Laboratory

Objective:

ICD-10:

Description:

Infusion of prothrombin complex concentrate can rapidly reverse the effects of a vitamin K antagonist like coumadin. This does not depend on hepatic synthetic capacity and can be infused using a smaller volume than fresh frozen plasma (FFP).

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