Description

Valls et al used dual-phase helical CT to determine if a pancreatic adenocarcinoma was resectable prior to surgery. The authors are from 3 hospitals in Barcelona.


Preoperative staging

 

Arterial invasion was defined as any direct tumor-to-vessel contiguity (contact with complete obliteration of the fat plane) even if contact is less than 50%

 

Venous invasion was defined as tumor-to-vessel circumferential contiguity >= 50%.

 

Liver metastases were nodular low attenutation lesions >= 1 cm in diameter which could not be identified to be a cyst or hemangioma.

 

Lymph nodes > 1.5 cm outside peripancreatic draining chains of the pancreas were considered malignant.

 

Peritoneal dissemination was diagnosed if there was substantial ascites and a large number of peritoneal nodules.

 

Criteria for unresectability - one or more of the following:

(1) liver metastasis

(2) metastases to regional or distant lymph nodes

(3) metastases to the omentum

(4) invasion of an adjacent organ excludng the duodenum

(5) arterial invasion or any tumor-to-artery contiguity

(6) massive venous invasion (tumor thrombus, obliteration of venous lumen)

(7) peritoneal dissemination

 

In 2002 the positive predictive value of resectability was 77% using dual-phase helical CT..

 

Reasons for unresectability that were not detected on the CT scan:

(1) small hepatic metastases

(2) vascular encasement/arterial invasion

(3) lymph node metastases


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