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Use of Fresh Frozen Plasma (FFP) to Reverse the Effects of a Vitamin K Antagonist

Specialty:

Hematology Oncology
Clinical Laboratory
Clinical Pharmacology
Clinical Laboratory

Objective:

ICD-10:

Description:

Infusion of fresh frozen plasma (FFP) can rapidly reverse the effects of a vitamin K antagonist like coumadin. This does not depend on hepatic synthetic capacity but may involve a considerable volume load. In addition, FFP may have a higher risk for infectious or other late complications.

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