Muntanola et al described the use of abdominal CT to detect lymphadenopathy and/or splenomegaly in patients with Rai Stage 0 chronic lymphocytic leukemia (CLL). This can help identify a group of patients who are at increased risk for clinical progression and who may benefit from more aggressive management. The authors are from the University of Barcelona in Spain.
Rai Stage 0 CLL consists of lymphocytosis without lymphadenopathy or splenomegaly. Detection of either would indicate understaging based on the clinical examination.
