Description

Normally the renal tubules influence the glomerular filtrate as it becomes urine. Disorders of renal tubular function may affect the osmolality of the urine. In isosthenuria the renal tubules are not functioning properly and do little to alter the glomerular filtrate.


 

Parameters:

(1) urine osmolality in mOsm per kg water

(2) plasma osmolality in mOsm per kg water

 

ratio of urine to plasma osmolality =

= (urine osmolality) / (plasma osmolality)

 

Term

Urine Osmolality

Urine to Plasma Osmolality Ratio

Example Urine Osmolality

isosthenuria

similar to plasma

0.9 to 1.05

235 to 330

hyposthenuria

more dilute than plasma

< 0.9

 

hypersthenuria

more concentrated than plasma

> 1.1

 

 

The specific gravity of isosthenuric urine is often around 1.008 to 1.010 but may be affected by a number of factors.

 


To read more or access our algorithms and calculators, please log in or register.