Both D-arabinitol and L-arabinitol are found normally in serum and urine, while D-arabinitol is a metabolite found in Candida species. An increase in the amount of D-arabinitol relative to L-arabinitol can be found in pediatric oncology patients with invasive candidiasis. The elevation may occur in advance of positive cultures, allowing early and more targeted therapy.
Patient Selection:
(1) children with cancer being treated with chemotherapy