A number of tumors may contain melanin pigment. The demonstration of melanin in a tumor does not guarantee that the tumor is a malignant melanoma.
Tumors that may contain melanin:
Clear cell carcinoma (melanoma of soft parts)
Melanotic schwannoma (psammomatous melanotic schwannoma)
Melanotic neurofibroma (pigmented neurofibroma)
Epithelioid malignant peripheral nerve sheath tumor
Pigmented ambeloblastic adenoma
Pigmented malignant ameloblastoma
PEComa (perivascular epithelioid cell tumor)
Angiomyolipoma
Lymphangioleiomyomatosis
Pigmented dermatofibrosarcoma protuberans (Bednar Tumor)
Melanotic neuroectodermal tumor of infancy
Pigmented cardiac paraganglioma
Pigmented basal cell carcinoma (BCC)
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Specialty: Hematology Oncology, Surgery, general, Dermatology
