UICC Criteria for Tumor Response Following Therapy

Purpose: To describe the response of a patient's tumor to therapy based on changes seen at 4 weeks after treatment.

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Evaluation

Are you evaluating a patient's tumor response to therapy?

Yes

Number of lesions at baseline that were measured (enter from 1 to 5)

Number of new lesions that have appeared by 4 weeks after therapy

Diameter of selected lesions at baseline

• diameter of first lesion

• diameter of second lesion

• diameter of third lesion

• diameter of fourth lesion

• diameter of fifth lesion

Diameter of selected lesions at 4 weeks

• diameter of first lesion

• diameter of second lesion

• diameter of third lesion

• diameter of fourth lesion

• diameter of fifth lesion

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Total tumor volume at baseline

Total tumor volume at 4 weeks after therapy

Post therapy tumor volume as a percent of the original volume

Have any single lesion showed progression (increase by 25%)?

Has progression been indicated by the appearance of new lesions?

Tumor response based on the change in tumor volume at 4 weeks

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Pharmacokinetic Test Dose to Detect Risk for Excessive Toxicity Prior to 5-Fluorouracil Therapy
Criteria For Diagnosis
- World Health Organization (WHO) Criteria for Tumor Response to Therapy
Severity, Prognosis, Stage
- World Health Organization (WHO) Criteria for Tumor Response to Therapy

Therapy

Options
- World Health Organization (WHO) Criteria for Tumor Response to Therapy
Selection
- World Health Organization (WHO) Criteria for Tumor Response to Therapy
- Pharmacokinetic Test Dose to Detect Risk for Excessive Toxicity Prior to 5-Fluorouracil Therapy
Dosage Adjustments
- Irinotecan Dosage Adjustment for Colon Cancer and Hepatic Dysfunction

Monitoring

Response To Therapy
- World Health Organization (WHO) Criteria for Tumor Response to Therapy
- Criteria for Metabolic Response to Therapy Seen on PET Scan
Disease Progression
- World Health Organization (WHO) Criteria for Tumor Response to Therapy

Specialty

Hematology Oncology
Surgery, general

Objective

response to therapy

ICD-10

C80.9 - Malignant neoplasm, primary site unspecified

Info

Purpose: To describe the response of a patient's tumor to therapy based on changes seen at 4 weeks after treatment.

Specialty: Hematology Oncology, Surgery, general

Objective: response to therapy

ICD-10: C80.9,

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