Tuberculosis in Children in HIV-Endemic Area of Africa

Are you evaluating a child in a developing country with weight loss, night sweats and/or chronic cough?

Yes

Age of the child

years

Is a smear positive for acid fast bacilli on Ziehl-Neelsen staining?

Yes

Is a mycobacterial culture positive for M. tuberculosis?

Yes

Is PCR positive for M. tuberculosis?

Yes

Is a TB skin test positive?

Yes

Is the chest X-ray suggestive for pulmonary tuberculosis?

Yes

Are caseating granulomas seen on biopsy?

Yes

Does the patient have a history of contact with a patient with tuberculosis?

Yes

Has the patient shown improvement after 2 weeks of antibiotic therapy?

Yes

Has the patient shown improvement after therapy with antituberculosis agents?

Yes

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10

Diagnosis of Tuberculosis in Children in HIV-Endemic Area of Africa

Purpose: To evaluate a child <= 12 years of age in a developing country for tuberculosis (TB) using the algorithm of van Rheenen.