Reasons for Failure of HIV Patient with Tuberculosis to Respond to Chemotherapy

Is the diagnosis of tuberculosis wrong?

Is the strain of tuberculosis resistant to the antituberculous therapy?

Has the patient developed bronchiectasis secondary to the tuberculosis?

Has the patient developed heart failure or other comorbid condition?

Does the patient have a superimposed pneumonia?

Has the patient developed a tumor?

Could the patient have the immune reconstitution syndrome associated with antiretroviral therapy?

Is the patient experiencing progression of the HIV disease?

Has the patient been nonadherent or poorly adherent to the drug regimen?

Has the patient had poor absorption of oral medications?

Does the medication have a reduced potency?