Description

Rothe et al reported an algorithm for detection of a urinary tract infection (UTI) in a hospitalized patient with bacteriuria. This can help guide patient management. The authors are from multiple institutions in Germany, Japan and London.


Patient selection: bacteriuria

 

F scores (one point each):

F1: fever at triage (with rigors or chills prior to presentation)

F2: failure or dysfunction of an organ system (brain, kidney, etc)

F3: focal urinary tract infection symptoms (acute dysuria, frequency, suprapubic tenderness, costovertebral angle pain or tenderness

 

3FS score =

= F1 + F2 + F3

 

Diagnosis

Criteria

asymptomatic bacteriuria

3FS negative

definitive SUTI

3FS positive; procalcitonin >= 0.25 ng/mL; positive blood culture; blood and urine cultures concordant

probable SUTI

3FS positive; procalcitonin >= 0.25 ng/mL; negative blood culture; F1+F2>=1; F3=1

probable SUTI

3FS positive; procalcitonin < 0.25 ng/mL; F1+F2>=1; F3=1

possible SUTI

3FS positive; procalcitonin >= 0.25 ng/mL; negative blood culture; F1+F2>=1; F3=0

possible SUTI

3FS positive; procalcitonin < 0.25 ng/mL; F1+F2>=1; F3=0

asymptomatic bacteriuria AND alternative focus

3FS positive; procalcitonin >= 0.25 ng/mL; positive blood culture; blood and urine cultures discordant; F3=0

urocystitis and alternative focus

3FS positive; procalcitonin >= 0.25 ng/mL; positive blood culture; blood and urine cultures discordant; F3=1

urocystitis

3FS positive; procalcitonin>= 0.25 ng/mL; negative blood culture; F1=0, F2=0, F3=1

urocystitis

3FS positive; procalcitonin < 0.25 ng/mL; F1=0, F2=0, F3=1

alternative or additional focus

3FS positive; evidence of infection elsewhere

 

where:

SUTI = UTI with systemic involvement

 

Asymptomatic bacteriuria does not require treatment.

Uncomplicated urocystitis requires antibiotic therapy with activity against urinary pathogen.

Systemic infection requires more aggressive management.


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