The product of serum triglycerides and fasting glucose can be used to identify a patient at increased risk for insulin resistance. This uses commonly available laboratory results.


(1) serum triglyceride concentration in mg/dL

(2) fasting glucose in mg/dL


TyG product =

= LN((serum triglyceride) * (glucose) / 2)



The values reported in Table 1 of Simental-Mendia do not match this equation. They do match LN((serum triglyceride) * (glucose)) / 2

Subsequent authors give TgG values similar to those given by the first equation.



The higher the TyG the greater the risk for insulin resistance.

Zhang et al reported a TyG >= 8.5 was associated with NAFLD.

Nor et al reported a TyG >= 8.52 as the optimal cutoff for insulin resistance in pediatric patients.

To get this cut-off with a fasting glucose of 99 mg/dL, the triglyceride is 99 mg/dL.

Simental-Mendia et al found the product to be sensitive but to have a low specificity.

To read more or access our algorithms and calculators, please log in or register.