Trigger Tool of Noorda et al for Adverse Drug Reactions (ADR) in an Elderly Patient with Polypharmacy: Abnormal Laboratory Tests

Description

Noorda et al reported a trigger tool for evaluating an elderly patient with polypharmacy and an adverse drug reaction (ADR). One group of adverse drug reactions involve abnormal laboratory test findings. The authors are from University Medical Centre Utrecht, Utrecht University, University of Groningen and The Netherlands Pharmacovigilance Centre Lareb.

Patient selection: geriatric patient with polypharmacy, admitted acutely to the hospital.

Adverse drug reaction: abnormal laboratory test findings

Abnormal Laboratory Test Results	Frequently Implicated Drugs
hyponatremia	thiazide or loop or potassium sparing diuretics; ACE-I, ARB, antidepressants
hypokalemia	thiazide or loop diuretic
hyperkalemia	potassium-sparing diuretics, ACE-I, ARB
hypoglycemia	insulin, oral antidiabetic drugs
hyperglycemia	systemic corticosteroids

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Trigger Tool of Noorda et al for Adverse Drug Reactions (ADR) in an Elderly Patient with Polypharmacy: Abnormal Laboratory Tests

Description

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