The Massachusetts General Hospital (MGH) developed a score for staging treatment-resistant depression.
Parameters:
(1) number of adequate trails of an antidepressant that the patient has not responded to
(2) number of these trials that were optimized
(3) electroconvulsive therapy (ECT)
Parameter |
Finding |
Points |
number of adequate trials with an antidepressant that were optimized |
(number) |
(number) * 1.5 |
number of adequate trials with an antidepressant that were not optimized |
(number) |
(number) |
ECT therapy |
not given |
0 |
|
given |
3 |
total number of adequate trials =
= (number optimized) + (number not optimized)
where:
• An adequate trial involves an adequate dose of an antidepressant for at least 6 weeks.
• Optimization involves attentions to duration, dose and augmentation.
• The total number of adequate trials indicates the number of different types of antidepressants that the patient has received.
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: dependent on the number of trials
• The higher the score the better the documentation of therapy resistance.
Purpose: To evaluate a patient for treatment-resistant depression using the staging score from the Massachusetts General Hospital.
Specialty: Psychiatry
Objective: severity, prognosis, stage
ICD-10: F32, F33,