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Description

People who eat squirrel brains rarely can develop transmissible spongiform encephalopathy (TSE, variant prion disease). The diagnosis may be delayed which impacts attempts to control the disease.


Clinical features:

(1) The patient has a history of eating squirrel brains.

(2) Other sources of prion disease excluded.

(3) The patient develops a spongioform encephalopathy with cognitive decline.

 

Protein 14-3-3 may be found in the CSF.


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