Transient pseudohypoaldosteronism may occur in patients with a disorder of the urnary tract. This occurs when there is a transient resistance of tubular epithelium to aldosterone.


Clinical features:

(1) renal salt-wasting with hyponatremia and hypovolemia

(2) hyperkalemia

(3) normal to elevated levels of aldosterone

(4) normal to elevated plasma renin activity

(5) metabolic acidosis

(6) onset associated with a urinary tract abnormality

(7) reversal of syndrome after correction of the urinary tract abnormality


Urinary tract abnormalities may include:

(1) pyelonephritis or other urinary tract infection

(2) urinary tract obstruction

(3) hydronephrosis

(4) other urinary tract abnormality


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