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Toxicogenetics of Paraoxonase (PON1) in Farmers Affected by Organophosphates Used in Sheep Dip

Specialty:

Clinical Pharmacology & Toxicology
Emergency Medicine & Critical Care
Emergency Medicine & Critical Care

Objective:

ICD-10:

Description:

Cherry et al correlated activity of enzymes involved in the metabolism of organophosphates with ill-health in farmers who dip sheep. Lower activity of paraoxonase (PON1) is associated with claims of ill health. The authors are from the University of Manchester and the Manchester Royal Infirmary.

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