4-aminobiphenyl is a human carcinogen. Metabolism in the body results in reactive metabolites which may interact with DNA. It can form adduct with albumin and hemoglobin.
Chemical class: arylamine (aromatic amine)
Cancers associated with 4-aminobiphenyl:
(1) urothelial carcinoma
(2) possibly hepatocellular carcinoma
(3) possibly other carcinomas
Exposures:
(1) industrial (discontinued)
(2) cigarette smoking
(3) laboratory workers
(4) food dye manufacturers
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