Description

Sho et al developed a score for identifying a premature infant at risk for necrotizing enterocolitis (NEC) totalis. This can help to identify a neonate who may require more aggressive management. The authors are from Childern's Hospital of Pittsburgh and the University of Pittsburgh.


 

Patient selection: premature neonate with necrotizing enterocolitis

 

Parameters:

(1) age in days

(2) serum creatinine in mg/dL

(3) serum phosphate in mEq/L

(4) platelet count

Parameter

Finding

Points

age

<= 7 days

0

 

>= 8 days

1

serum creatinine

<= 0.8 mg/dL

0

 

> 0.8 mg/dL

1

serum phosphate

<= 6.0 mEq/L

0

 

> 6.0 mEq/L

1

platelet count

>= 150,000 per µL

0

 

80,000 to 149,999

1

 

< 80,000 per µL

2

 

totalis score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 5

• The higher the score the more likely that the patient will develop NEC totalis.

 

Performance:

• A score >= 3 had a sensitivity of 92% and specificity of 78% for NEC totalis.

• A score >= 4 had a sensitivity of 58% and specificity of 97%.

 


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