The total or corrected urea clearance (KT) consists of the Kt/V corrected for residual renal urea clearance (Kru).


For Hemodialysis Twice Weekly Schedule


KT =

= (Kt/V) + (9.5 * (Kru / (total body water)))


For Hemodialysis Thrice Weekly Schedule


KT =

= (Kt/V) + (5.5 * (Kru / (total body water)))



• Grotch (1991) uses 4.5 instead of 5.5 (Daugirdas) for thrice weekly hemodialysis


The Kru measured before starting a hemodialysis protocol is likely to drop after the hemodialysis has begun, and may reach 0.


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