The ratio of direct to total serum bilirubin can help in predicting the cause of jaundice. The total serum bilirubin must exceed 2.5 mg/dl to produce clinical jaundice.
direct bilirubin-to-total bilirubin ratio =
= ((serum direct bilirubin) / (serum total bilirubin))
constitutional hyperbilirubinemia (Gilbert's, Crigler-Najjar, etc.)
hepatocellular disease more likely than extrahepatic obstruction
may be either hepatocellular disease or extrahepatic obstruction
extrahepatic obstruction more likely than hepatocellular disease
To read more or access our algorithms and calculators, please log in or register.
Purpose: To use the ratios of liver function tests in the diagnosis of liver disease.
Objective: laboratory tests