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Total Plasma Exchange in a Patient with Progressive Multifocal Leukoencephalopathy (PML) Associated with Natalizumab Therapy

Specialty:

Clinical Laboratory
Infectious Diseases
Toxicology

Objective:

ICD-10:

Description:

Patients with multiple sclerosis (MS) who are treated with natalizumab are at risk for developing Progressive Multifocal Leukoencephalopathy (PML). Immune reconstitution is needed to clear the infection, and the monoclonal antibody can be cleared faster with total plasma exchange.

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