For some drugs the total lifetime exposure may have some clinical significance. This is somewhat analogous to number of pack years of smoking.


NOTE: This is a simplified version assuming constant dosing and perfect compliance without interruption. A realistic version would need to take into account variations that might arise.



(1) number of units in dose (mg or grams)

(2) number of doses per day

(3) number of years of therapy


total lifetime exposure in units =

= (units per dose) * (dose per day) * (365 days) * (number of years)


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