TNM Classification of Neuroblastoma

TNM

Designation

Description

T

TX

primary tumor cannot be assessed

T0

no evidence of primary tumor

T1

single tumor <= 5 cm in greatest dimension

T2

single tumor > 5 cm but <= 10 cm in greatest dimension

T3

single tumor > 10 cm in greatest dimension

T4

multicentric tumors occurring simultaneously

N

NX

regional lymph nodes cannot be assessed

N0

no metastasis to regional lymph nodes

N1

regional lymph node metastasis

M

MX

presence of distant metastasis cannot be assessed

M0

no distant metastasis

M1

distant metastasis present

Stage

TNM

I

T1, N0, M0

II

T2, N0, M0

III

T1, N1, M0

T2, N1, M0

T3, N0 or N1, M0

IVA

T1, N0 or N1, M1

T2, N0 or N1, M1

T3, N0 or N1, M1

IVB

T4, N0 or N1, M0 or M1