A patient with Marfan's syndrome is at increased risk for aneurysm and dissection of the thoracic aorta. Pre-emptive surgical repair can be considered when certain clinical features are present.
Parameters:
(1) diameter of the aorta in cm
(2) risk factors for aneurysm dissection
Risk factors for progression of the thoracic aortic aneurysm:
(1) family history of dissection
(2) dilation rate > 3-5 mm per year
(3) severe aortic regurgitation
(4) desired pregnancy
Aneurysm Diameter
Number of Risk Factors
Surgery
>= 5.0 cm
0
yes
>= 4.5 cm
>= 1
yes
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