TIGAR-O designates major presdisposing risk factors for chronic pancreatitis.
Patient selection: chronic pancreatitis
Code
|
Etiology
|
T
|
toxic-metabolic
|
I
|
idiopathic
|
G
|
genetic (hereditary)
|
A
|
autoimmune
|
R
|
recurrent
|
O
|
obstructive
|
Toxic-metabolic: alcohol, tobacco, hypercalcemia
Idiopathic: early onset, late onset and tropical
Genetic hereditary (cationic trypsinogen mutation), CFTR mutation (cystic fibrosis), SPINK1 mutation, alpha-1 antitrypsin deficiency
Autoimmune: isolated or associated with other autoimmune disorder
Recurrent: postnecrotic, recurrent, ischemic/vascular
Obstructive: pancreas divisum, intrapapillary mucinous tumor, ductal adenocarcinoma, other