Some patients with Graves' disease will show diffuse thymic hyperplasia.
(1) signs and symptoms of Graves' disease (thyrotoxicosis)
(2) presence of diffuse thymic hyperplasia
(3) variable myopathy with fluctuating limb weakness
In this setting the myopathy may represent either:
(1) thyrotoxic myopathy (pseudo-myasthenia)
(2) true myasthenia gravis
Medical therapy of the thyrotoxicosis results in regression of thymic hyperplasia and improvement in muscle symptoms. In true myasthenia the muscle weakness persist or get worse.
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Specialty: Hematology Oncology, Clinical Laboratory, Endocrinology