Yoo et al reported a score for evaluating a patient for thrombotic microangiopathy. The authors are from Yonsei University, Korea University and affiliated hospitals.
Parameters (based on screening criteria for schistocytosis on the ADVIA 120):
(1) RDW in percent
(2) hemoglobin distribution width (HDW) in percent
(3) percentage of microcytes (volume less than 60 fL)
(4) percentage of hyperchromatic red blood cells
(5) platelet count in 10^9/L
Parameter
Finding
Points
RDW
<= 15%
0
> 15%
1
HDW
<= 3.2%
0
> 3.2%
1
microcytes
< 0.4%
0
>= 0.4%
1
hyperchromatic RBCs
< 1.9%
0
>= 1.9%
1
platelet count
>= 140 * 10^9/L
0
< 140 * 10^9/L
1
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• The higher the score the greater the risk of a thrombotic microangiopathy.
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