The Sydney System can be used to accurately describe the extent and histologic appearance of gastritis. The scheme was developed by a Working Party designated at the 9th World Congresses in Gastroenterology.
Parameters:
(1) etiology (prefix term)
(2) topography and special forms/associations (core term)
(3) morphology (suffix term)
Etiological classification:
(1) Helicobacter pylori
(2) autoimmune-associated
(3) idiopathic
(4) drug-associated
(5) other gastric irritant
(6) bacterial, other than Helicobacter
(7) viral
(8) parasitic
(9) fungal
Topography:
(1) corpus
(2) antrum
(3) both corpus and antrum (pangastritis)
Temporal:
(1) acute (acute inflammation with no or minimal chronic inflammation)
(2) chronic (lymphoplasmocytic predominant)
(3) special forms (with a recognizable pattern)
Special forms:
(1) eosinophilic gastritis
(2) lymphocytic gastritis
(3) Crohn's disease associated granulomatous gastritis
(4) sarcoidosis
(5) idiopathic granulomatous gastritis
(6) reactive gastritis
(7) radiation-associated gastritis
(8) phlegmonous gastritis
(9) post-gastrectomy associated
Morphological parameters determined separately for the corpus and antrum:
(1) chronic inflammation
(2) activity (acute neutrophilic infiltrate)
(3) atrophy
(4) intestinal metaplasia
(5) number of bacteria morphologically consistent with Helicobacter pylori
Grading for each morphologic parameter:
(1) none
(2) mild
(3) moderate
(4) severe
Additional non-graded variables:
(1) nonspecific
(2) specific
Specialty: Gastroenterology, Infectious Diseases, Surgery, general