Davis et al listed 7 nephropathies associated with sickle cell disease or trait. The authors are from the Armed Forces Institute of Pathology (AFIP) in Washington, D.C.


Nephropathies associated with sickle cell disease or trait:

(1) unilateral hematuria

(2) papillary necrosis

(3) nephrotic syndrome

(4) renal infarction

(5) inability to concentrate urine

(6) pyelonephritis

(7) renal medullary carcinoma


The differential diagnosis of these conditions include conditions not related to sickle cell disease such as nephrolithiasis or diabetic nephrosclerosis.


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