The SAHA syndrome consists of seborrhea, acne, hirsutism and alopecia in women. These cutaneous findings are associated with either excessive serum concentrations of androgens or an excessive response to normal concentrations of circulating androgens.


Key features:

(1) seborrhea

(2) acne

(3) hirsutism

(4) alopecia


Additional findings may include:

(1) obesity

(2) cystic mastitis

(3) reduced fertility


There are 4 types based on the underlying cause:

(1) ovarian (often polycystic ovary disease)

(2) adrenal

(3) hyperprolactinemic

(4) idiopathic


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