Description

The Patient Health Questionnaire 2 (PHQ-2) is a brief screen for depression that can be used in primary care. It uses the 2 questions for depression from the patient questionnaire of PRIME-MD (see 18.25.01).


 

NOTE: PRIME-MD is a trademark of Pfizer Inc, which also holds the copyright. For a complimentary copy of PHQ materials that can be reproduced contact Dr Spitzer at rls8@columbia.edu.

 

Interval: past 2 weeks

 

Questions: 2

Frequency over the past 2 weeks

Points

not at all

0

several days

1

more than half

2

nearly every day

3

 

where:

• The severity of the depressive symptoms is not graded. This opens the possibility of a severity score with (severity points) * (frequency points).

• In the implementation I used a raw number of days. The alternative is a 4 point Likert scale.

 

total score =

= SUM(points for the 2 questions)

 

Interpretation:

• minimum score: 0

• maximums score: 6

• The higher the score the more likely the patient has a depressive disorder.

• The highest Youden index is a score >= 3.

 

Performance to detect any depressive illness (performance for detecting major depression is shown in Table 2, page 1287).

 

PHQ-2

Sensitivity

Specificity

0

 

 

1

91%

65%

2

82%

80%

3

62%

95%

4

51%

98%

5

31%

98.7%

6

12%

99.8%

 


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