Claus et al calculated the cumulative risk for a woman developing breast cancer by a certain age if she has a family history of breast cancer. The following tables apply if the patient's mother and one aunt (either maternal or paternal) develop breast cancer. The study is based on the data from the Cancer and Steroid Hormone Study conducted by the Centers for Disease Control.
Mother and Maternal Aunt (Table 5, page 647))
Age of Mother at Diagnosis: 20-29
|
Age of Maternal Aunt at Diagnosis |
Patient |
20-29 |
30-39 |
40-49 |
50-59 |
60-69 |
70-79 |
29 |
0.019 |
0.018 |
0.017 |
0.016 |
0.014 |
0.012 |
39 |
0.064 |
0.062 |
0.058 |
0.054 |
0.047 |
0.040 |
49 |
0.153 |
0.148 |
0.141 |
0.129 |
0.115 |
0.098 |
59 |
0.273 |
0.265 |
0.251 |
0.232 |
0.206 |
0.178 |
69 |
0.382 |
0.371 |
0.353 |
0.327 |
0.293 |
0.254 |
79 |
0.450 |
0.437 |
0.417 |
0.388 |
0.349 |
0.305 |
Age of Mother at Diagnosis: 30-39
|
Age of Maternal Aunt at Diagnosis |
Patient |
20-29 |
30-39 |
40-49 |
50-59 |
60-69 |
70-79 |
29 |
0.018 |
0.017 |
0.016 |
0.014 |
0.011 |
0.009 |
39 |
0.061 |
0.058 |
0.053 |
0.046 |
0.039 |
0.031 |
49 |
0.147 |
0.139 |
0.128 |
0.112 |
0.094 |
0.076 |
59 |
0.262 |
0.249 |
0.229 |
0.203 |
0.172 |
0.140 |
69 |
0.367 |
0.350 |
0.323 |
0.287 |
0.246 |
0.204 |
79 |
0.433 |
0.414 |
0.383 |
0.343 |
0.296 |
0.248 |
Age of Mother at Diagnosis: 40-49
|
Age of Maternal Aunt at Diagnosis |
Patient |
20-29 |
30-39 |
40-49 |
50-59 |
60-69 |
70-79 |
29 |
0.017 |
0.015 |
0.013 |
0.011 |
0.009 |
0.006 |
39 |
0.057 |
0.052 |
0.046 |
0.038 |
0.030 |
0.022 |
49 |
0.137 |
0.125 |
0.110 |
0.092 |
0.073 |
0.056 |
59 |
0.245 |
0.225 |
Specialty: Hematology Oncology, Surgery, general, Obstetrics & Gynecology |