Argenziano et al developed a checklist for use during epiluminescent microscopic examination of a melanocytic skin lesion. This can help identify a lesion that has an increased risk of being a malignant melanoma. The authors are from the Universities of Naples and Florence in Italy.
Parameters:
(1) pigment network
(2) color
(3) vascular pattern
(4) streaks
(5) blotches
(6) dots and globules
(7) regression pattern
Parameter |
Finding |
Points |
---|---|---|
pigment network |
typical |
0 |
|
atypical |
2 |
color |
no gray-blue areas |
0 |
|
gray-blue areas present |
2 |
vascular pattern |
typical |
0 |
|
atypical |
2 |
streaks |
absent |
0 |
|
present |
1 |
blotches |
absent |
0 |
|
present |
1 |
dots and globules |
absent |
0 |
|
regular |
0 |
|
irregular |
1 |
regression pattern |
absent |
0 |
|
present |
1 |
score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 10
• A score >= 3 indicates a lesion at increased risk for being a melanoma. Only melanomas had a score >= 8 in the original series.
Performance:
• Overall diagnostic sensitivity 85-95% with specificity 45-75%, depending on experience of the observer.
Purpose: To evaluate a pigmented skin lesion using epiluminescence microscopy and the 7-point checklist of Argenziano et al.
Specialty: Dermatology, Hematology Oncology
Objective: laboratory tests, other testing, criteria for diagnosis
ICD-10: C43, D22,