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The Corrected Count Increment (CCI) and the Increment in Platelet Count after Platelet Transfusion

Purpose:

To measure increase in platelet count after platelet transfusion, in order to see if increase expected is achieved.

Specialty:

Blood Banking/Transfusion Medicine

Objective:

other testing, dosage calculations, dosage adjustments

ICD-10:

Z51.3, D69

Description:

The increment in platelets following platelet product transfusion is directly related to dose given, unless there is increased removal of the transfused platelets. The Corrected Count Index (CCI) is intended to differentiate between immune and nonimmune loss, with a post-transfusion specimen collected 1 hour after the platelet product transfusion. With immune thrombocytopenia there is little increment in the platelet count seen at 1 hour, whereas with nonimmune mechanisms the platelet count at 1 hour is relatively normal.

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