Patient selection: systemic juvenile idiopathic arthritis
Parameters:
(1) temperature in °C (fever)
(2) evanescent erythematous rash
(3) generalized lymphadenopathy (>= 3 lymph node stations)
(4) hepatomegaly and/or splenomegaly
(5) serositis (pleuritis, pericarditis, or peritonitis)
(6) hemoglobin in g/dL (anemia)
(7) platelet count in 10^9/L
(8) serum ferritin in ng/mL
|
Parameter
|
Finding
|
Points
|
|
body temperature
|
< 37°C
|
0
|
|
|
37 to 38 °C
|
1
|
|
|
38.1 to 39 °C
|
2
|
|
|
39.1 to 40 °C
|
3
|
|
|
> 40°C
|
4
|
|
erythematous rash
|
no
|
0
|
|
|
yes
|
1
|
|
generalized lymphadenopathy
|
no
|
0
|
|
|
yes
|
1
|
|
hepatomegaly or splenomegaly
|
no
|
0
|
|
|
yes
|
1
|
|
serositis
|
no
|
0
|
|
|
yes
|
1
|
|
hemoglobin
|
>= 9 g/dL
|
0
|
|
|
< 9 g/dL
|
1
|
|
platelet count or ferritin
|
PC <= 600 * 10^9/L AND serum ferritin <= 500 ng/mL
|
0
|
|
|
PC > 600 * 10^9/L
|
1
|
|
|
serum ferritin > 500 ng/mL
|
1
|
where:
• The temperature cut-points as published overlapped at 38°C and 39°C.
• Tibaldi et al used a temperature range of 37.5 to 38°C instead of 37 to 38°C
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 10
• The higher the score the greater the systemic activity.
