System of Sanders et al for Grading Transfusion-Associated Acute Lung Injury (TRALI)

Description

Sanders et al graded transfusion-associated acute lung injury (TRALI) using a system modeled after the Common Toxicity Criteria (CTC) for adverse effects of cancer therapy. The authors are from St. Jude Children's Research Hospital, University of Tennessee and McMaster University.

Parameters for TRALI severity:

(1) pulmonary symptoms (shortness of breath, etc)

(2) radiographic findings on AP chest X-ray

(3) oxygenation

Radiographic Findings	Pulmonary Symptoms	Oxygenation	Grade
normal	none	normal	0
bilateral infiltrates	none	normal	1
bilateral infiltrates	mild	oxygen saturation >= 90%	2
bilateral infiltrates	moderate	oxygen saturation < 90%; supplemental oxygen required	3
bilateral infiltrates	respiratory failure	ventilatory support	4
NA	NA	death	5

In pure TRALI there should be no evidence of heart failure or circulatory overload.

To read more or access our algorithms and calculators, please log in or register.

System of Sanders et al for Grading Transfusion-Associated Acute Lung Injury (TRALI)

Description

Specialty