System of Sanders et al for Grading Hypotension Associated with Transfusion Therapy

Description

Sanders et al graded a hypotensive reaction associated with transfusion therapy using a system modeled after the Common Toxicity Criteria (CTC) for adverse effects of cancer therapy. The authors are from St. Jude Children's Research Hospital, University of Tennessee and McMaster University.

Inclusions: hypotension associated with ACE inhibitor therapy (see 05.14.19)

Exclusions: hypotension due to anaphylaxis, sepsis, circulatory failure, etc.

Parameters:

(1) reduction in blood pressure

(2) clinical findings (bradycardia, dyspnea, other)

(3) therapy

Blood Pressure	Clinical Findings	Therapy	Grade
none	none	none	0
mild and transient drop	none	none	1
moderate drop	mild; no physiologic impact	< 24 hours with fluid replacement and symptomatic care	2
moderate to severe drop	moderate; with no physiologic impact	>= 24 hours with fluid replacement and symptomatic care	3
shock	one or more organ failures	intensive, may be admitted to the ICU	4
shock	death	NA	5

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Description

Specialty

ICD-10