False Negative Serologic Tests for Syphilis in HIV-Infected Patient

Does the patient show severe immunosuppression or clinical AIDS?

Has the patient been engaged in high risk sexual behavior?

Has the patient had close contact with someone who engages in high risk sexual behavior?

Does the patient have a chancre or a history of one?

Does the patient have a systemic illness with a generalized rash?

Does a biopsy from a lesion show a lymphoplasmacytic perivascular infiltrate?

Does the patient give weak, negative or atypical reactions in serologic tests?

Does the patient show low levels of serum immunoglobulins?

Results on serologic tests for syphilis